Lariam, Mefloquine is an antimalarial medication used primarily for the prevention and treatment of malaria, a disease caused by parasites transmitted through the bite of an infected mosquito. Mefloquine is effective against malaria parasites resistant to other antimalarial drugs, making it a valuable option in areas where resistance is a concern.
Mechanism of Action
Mefloquine works by interfering with the growth and reproduction of malaria parasites in the red blood cells of the infected person. This action inhibits the parasite's life cycle, preventing the disease from progressing and alleviating symptoms.
Common Uses
Prevention of Malaria: Taken before, during, and after traveling to areas where malaria is common.
Treatment of Malaria: Used to treat acute cases of malaria, especially those caused by drug-resistant strains.
Dosage Instructions
For prevention, the adult dose is typically 250 mg once a week. It should be started 1-2 weeks before traveling to a malaria-endemic area, continued weekly during the stay, and then taken for 4 weeks after leaving the area. For treatment of malaria, the dosage can vary, but a common regimen involves a higher initial dose followed by additional doses. Always follow your healthcare provider's instructions for dosage and duration.
Benefits
Effective in preventing and treating malaria, including strains resistant to other medications.
Convenient weekly dosing for prevention.
Potential Side Effects
While mefloquine is effective, it can have potential side effects, including:
Nausea and vomiting.
Dizziness and headache.
Sleep disturbances and vivid dreams.
Anxiety and mood changes.
Rarely, more serious psychiatric effects like depression or psychosis.
It's important to discuss the risks and benefits of mefloquine with your healthcare provider, especially if you have a history of mental health issues.
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