Meniace-S, Betahistine is a medication commonly used to treat vertigo associated with Ménière's disease, a disorder of the inner ear that can lead to dizzy spells (vertigo) and hearing loss. Betahistine is thought to improve blood flow in the inner ear, which helps alleviate the symptoms of vertigo, tinnitus (ringing in the ears), and hearing loss associated with this condition.
Mechanism of Action
Betahistine primarily works by acting as a histamine analogue, which means it mimics the action of histamine. It acts predominantly on the histamine H1 receptors and has a slight effect on H3 receptors. The medication increases the blood flow in the inner ear, which reduces the buildup of fluid (endolymph) that contributes to the typical symptoms of Ménière's disease. Additionally, betahistine may facilitate neurotransmission in the vestibular nuclei, which are part of the brain that helps control balance.
Common Uses
Ménière's Disease: Betahistine is primarily used to reduce the frequency and intensity of vertigo attacks associated with Ménière's disease. It is also beneficial in managing associated symptoms like tinnitus and progressive hearing loss.
Dosage Instructions
Adults: The typical starting dose is 8 to 16 mg taken orally three times a day, preferably with meals to enhance absorption and reduce gastrointestinal side effects.
The dose may be adjusted based on the severity of the symptoms and the individual response to treatment. Maximum doses can go up to 48 mg per day.
Patients should follow their healthcare provider's instructions closely and maintain regular follow-ups to adjust the dose as needed.
Benefits
Reduces the severity and frequency of vertigo episodes.
Can alleviate tinnitus and help prevent hearing deterioration in people suffering from Ménière's disease.
Has a relatively good safety profile, especially compared to other treatments for similar symptoms.
Potential Side Effects
While betahistine is generally well-tolerated, some individuals may experience side effects, including:
Gastrointestinal disturbances like nausea and mild gastric upset.
Headaches.
Rarely, allergic reactions can occur, which might include rash, itching, or swelling.
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