Sildenafil Tab Usage Guide: Benefits and Side Effects

Sildenafil, widely known under the brand name Viagra, is a medication primarily used for treating erectile dysfunction (ED) and pulmonary arterial hypertension.

Mechanism of Action
Sildenafil works by inhibiting an enzyme called phosphodiesterase type 5 (PDE5). This inhibition leads to an increase in the levels of cyclic guanosine monophosphate (cGMP), which relaxes the smooth muscle cells in the blood vessels of the penis and lungs. For ED, this results in improved blood flow to the penis, facilitating an erection. In pulmonary hypertension, it reduces the pulmonary artery pressure.

Common Uses
Erectile Dysfunction: Sildenafil is most commonly used to treat ED, helping to achieve and maintain erections.
Pulmonary Arterial Hypertension: It is also prescribed to manage this condition, improving exercise capacity and delaying clinical worsening.

Dosage Instructions
For Erectile Dysfunction: The typical starting dose is 50 mg, taken about one hour before sexual activity. However, it can be taken anywhere from 30 minutes to 4 hours before. The dose may be adjusted based on effectiveness and toleration.
For Pulmonary Hypertension: The dosing can vary, and it's essential to follow a healthcare provider's specific instructions.

Benefits
Erectile Dysfunction: Sildenafil significantly improves the ability to gain and sustain an erection for sexual activity.
Pulmonary Hypertension: It improves exercise capacity and can reduce symptoms.

Potential Side Effects
Common side effects include headaches, flushing, indigestion, nasal congestion, and dizziness. Rare but severe side effects can include vision problems, hearing loss, or an erection that won’t go away (priapism). It's important to seek medical attention if experiencing severe or persistent side effects.

Additional Information
Sildenafil should not be used with certain medications, especially nitrates used for chest pain, as this can cause a dangerous drop in blood pressure.

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