Lobeglitazone is a medication belonging to the class of drugs known as thiazolidinediones (TZDs), used for the treatment of type 2 diabetes. It works by increasing the body's sensitivity to insulin, a hormone that regulates blood sugar levels. Lobeglitazone activates peroxisome proliferator-activated receptor gamma (PPAR-γ), a receptor found in fat cells, which helps regulate glucose and fat met..