Mechanism of Action Orfil SR Tab, Valproate Sodium is an anticonvulsant and mood-stabilizing medication commonly used to treat seizure disorders, bipolar disorder, and to prevent migraines. It works by increasing the levels of gamma-aminobutyric acid (GABA) in the brain, a neurotransmitter that helps calm nerve activity. By stabilizing electrical activity in the brain, Valproate Sodium reduces t..