Mechanism of Action Ulcerlmin Tab, Sucralfate is a medication primarily used to treat and prevent ulcers in the gastrointestinal tract. It works by forming a protective barrier over ulcers and damaged mucosal areas. When taken, sucralfate reacts with hydrochloric acid in the stomach to form a sticky, viscous substance that adheres to the ulcer site. This barrier protects the ulcer from further i..