Daonil, Glibenclamide, also known as glyburide in some regions, is a medication used to treat type 2 diabetes mellitus. It belongs to a class of drugs called sulfonylureas, which work by increasing insulin production in the pancreas. This process helps lower blood sugar levels and is most effective when combined with diet and exercise.
Mechanism of Action
Glibenclamide stimulates the beta cells in the pancreas to release more insulin. Insulin is the hormone responsible for regulating blood sugar levels by facilitating the movement of sugar from the blood into the body's cells. This action helps to lower blood glucose levels, making glibenclamide an effective treatment for managing type 2 diabetes.
Common Uses
Treatment of type 2 diabetes in cases where diet and exercise alone have not been sufficient to control blood sugar levels.
Sometimes used in combination with other diabetes medications to achieve better blood sugar control.
Dosage Instructions
The dosage of glibenclamide can vary depending on individual needs and blood sugar levels. The initial dose is often low, starting at 2.5 mg to 5 mg taken once daily with breakfast or the first main meal. The dose may be adjusted based on the patient's response, but it's crucial to follow the healthcare provider's instructions and not to adjust the dose on your own.
Benefits
Effective in lowering blood sugar levels in people with type 2 diabetes.
Can be taken as a single daily dose, simplifying the treatment regimen.
May be combined with other diabetes medications for improved blood sugar control.
Potential Side Effects
While glibenclamide is generally well-tolerated, some individuals may experience side effects, including:
Low blood sugar (hypoglycemia), especially if meals are skipped.
Weight gain.
Nausea.
Dizziness.
Skin rash.
It's important to monitor blood sugar levels regularly and to be aware of the signs of hypoglycemia.
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