Livalo, Pitavastatin calcium, marketed under the name Livalo among others, is a statin medication used primarily to manage cholesterol levels and reduce the risk of cardiovascular disease. It's known for its effectiveness in lowering bad cholesterol (LDL) and triglycerides while potentially increasing good cholesterol (HDL).
Mechanism of Action
Pitavastatin calcium works by inhibiting the enzyme HMG-CoA reductase, which plays a crucial role in cholesterol synthesis in the liver. By blocking this enzyme, pitavastatin effectively lowers the level of LDL cholesterol and triglycerides in the blood while also potentially raising HDL cholesterol levels.
Common Uses
Cholesterol Management: Primarily used to lower levels of LDL cholesterol and triglycerides.
Cardiovascular Risk Reduction: Helps reduce the risk of heart attacks, strokes, and other cardiovascular complications in patients at high risk.
Dosage Instructions
The dosage of pitavastatin calcium can vary based on the patient's individual needs, the target LDL levels, and the specific treatment goals:
Adults: The typical starting dose is 2 mg once daily in the evening, which can be adjusted up to 4 mg based on the patient’s response and clinical evaluation.
Elderly and patients with renal impairment: A lower starting dose may be recommended.
Pitavastatin should be taken consistently at the same time each day to maintain stable blood levels.
Benefits
Effectively lowers LDL cholesterol and triglycerides.
May help raise HDL cholesterol.
Contributes to a reduced risk of heart disease and stroke.
Potential Side Effects
While pitavastatin is generally well-tolerated, some individuals may experience side effects, including:
Muscle pain or weakness.
Digestive issues such as constipation or diarrhea.
Possible liver enzyme elevation.
Rarely, it can lead to more serious conditions like rhabdomyolysis or severe liver damage.
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