Lefdac Tab(Leflunomide) Usage Guide: Benefits and Side Effects

Lefdac, Leflunomide is a disease-modifying antirheumatic drug (DMARD) commonly used to treat rheumatoid arthritis and psoriatic arthritis. It helps reduce inflammation and slow the progression of the disease, thereby improving joint function and reducing pain.

Mechanism of Action
Leflunomide works by inhibiting the enzyme dihydroorotate dehydrogenase, which is necessary for the synthesis of pyrimidine, a nucleotide vital for DNA and RNA production. This inhibition results in a decrease in lymphocyte proliferation, which is crucial for the immune response that contributes to rheumatoid arthritis and psoriatic arthritis inflammation.

Common Uses
Rheumatoid Arthritis: Reduces symptoms such as joint swelling, pain, and helps prevent further joint damage.
Psoriatic Arthritis: Helps manage symptoms and prevents damage to the joints often affected by this condition.

Dosage Instructions
The typical starting dose for leflunomide is one 100 mg tablet once daily for three days, followed by a maintenance dose of 20 mg once daily. However, depending on the patient’s tolerance and the severity of the disease, the maintenance dose may be adjusted to 10 mg daily. It's important to follow a healthcare provider's instructions carefully and to have regular monitoring to adjust the dose as necessary and to check for potential side effects.

Benefits
Effectively reduces inflammation and pain in the joints.
Slows down the progression of joint damage in arthritis.
Improves physical function and quality of life for those with arthritis.

Potential Side Effects
While leflunomide is effective, it can cause side effects, which include:

Diarrhea.
Elevated liver enzymes (indicating possible liver damage).
Hair loss.
Rash.
Rarely, severe lung infections and blood pressure increases.

#류마이드정
#Rheumide Tab
#레플루노미드
#Leflunomide
#RheumatoidArthritis
#PsoriaticArthritis
#DMARD
#ArthritisTreatment

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