Biodornaze, Streptokinase and streptodornase are two enzymes often combined in medical treatments to facilitate the breakdown and removal of blood clots and necrotic tissue. Streptokinase is widely known for its role in treating thrombosis (blood clots) by converting plasminogen to plasmin, which breaks down clots. Streptodornase, on the other hand, is used to digest necrotic tissue and reduce v..